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Category: Science
Date: 06/30/12 09:15 AM

13 Responses to How Pain Relievers Work

  1. Profile photo of Matwix_2004
    Matwix_2004 Male 18-29
    2551 posts
    June 29, 2012 at 5:26 am
    Link: How Pain Relievers Work - SCIENCE!
  2. Profile photo of 5Cats
    5Cats Male 50-59
    33145 posts
    June 30, 2012 at 9:30 am
    Oooo! Learning is fun!

    (I`ve often wondered how this works, thx!)
  3. Profile photo of drips
    drips Male 30-39
    904 posts
    June 30, 2012 at 10:41 am
    About half-way through that video I started to suspect a screamer. What a solid misdirect that would have been.
  4. Profile photo of onoffonoffon
    onoffonoffon Male 30-39
    2383 posts
    June 30, 2012 at 12:28 pm
    Wish they would have covered Tylenol.
  5. Profile photo of Lednar
    Lednar Male 18-29
    109 posts
    June 30, 2012 at 4:55 pm
    The pain causing bunny rabbit attacks again!
  6. Profile photo of keith2
    keith2 Male 30-39
    2591 posts
    June 30, 2012 at 8:09 pm
    This is crap! Yes, I`m being a desk chair warrior here: Most people take tylenol, and naproxin sodium. But they would much rather get their hands on some VICODIN! How does that work? Crap video! Nobody takes asprin or ibuprofen, thats what butthole doctors give you instead of the good stuff. Doesn`t work at all except make your stomach hurt.
  7. Profile photo of Fleaman1797
    Fleaman1797 Male 18-29
    718 posts
    June 30, 2012 at 8:12 pm
    No one. NO ONE should take Tylenol. its killed FAR more people then most any other drug and its a worthless HORRIBLE drug. it destroys your liver and its not even for a fair trade (it doesnt work very well) it should be taken off the market, but of course it wont be.
  8. Profile photo of Draculya
    Draculya Male 40-49
    14657 posts
    July 1, 2012 at 5:28 am
    "Wish they would have covered Tylenol."

    Allow me to do so. Tylenol is a brand of painkiller of varying formulations. Tylenol`s main active ingredient is acetaminophen (a.k.a. paracetamol), which like aspirin and ibuprofen, is classed as a NSAID, although it has weaker anti-inflammatory action. Acetaminophen selectively blocks COX-2 which, as the video says, metabolises arachidonic acid to prostaglandin H2.
  9. Profile photo of JaLacaob
    JaLacaob Male 18-29
    1647 posts
    July 1, 2012 at 9:11 am
    Draculya: The pharmacist in me cannot let this go as it is. Acetaminophen is NOT an NSAID (Non-steroidal anti-inflammatory drug). It is in fact classified as an analgesic, which does not help inflammation and pretty much just blocks pain.

    Fleaman1797: It`s cheap. It does work. It won`t kill you if you don`t take too much of it, much like anything else in life. Don`t use it every time you break a nail, and don`t think you can take a whole load of it at one time and you`ll be fine.
  10. Profile photo of JaLacaob
    JaLacaob Male 18-29
    1647 posts
    July 1, 2012 at 9:15 am
    keith2: Take it with food. Vicodin is made of hydrocodone and.. guess what? Acetaminophen. They hydrocodone messes with your brain`s receptors rather than the active slots on your nociceptors.
  11. Profile photo of JaLacaob
    JaLacaob Male 18-29
    1647 posts
    July 1, 2012 at 9:20 am
    onoffonoffon: Acetaminophen (Tyelnol) works by basically blocking the COX from the video (Cox blocked?... anyway...) but it`s not blocking them in the same place. It`s blocking COX enzymes in the central nervous system rather than out at the nociceptors, aka, your spine/brain areas. It`s also not a terribly well understood drug, so there are other things going on there, as well, that are not actually scientifically proven.
  12. Profile photo of han5nah
    han5nah Female 13-17
    735 posts
    July 1, 2012 at 4:39 pm
  13. Profile photo of keith2
    keith2 Male 30-39
    2591 posts
    July 2, 2012 at 7:52 am
    Thanks JaLacoab for the shxtty explanation, I am enlightened by your knowledge.

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