How Pain Relievers Work

Submitted by: Matwix_2004 4 years ago Science

SCIENCE!
There are 12 comments:
Male 2,592
Thanks JaLacoab for the shxtty explanation, I am enlightened by your knowledge.
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Female 735
Awesome!
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Male 1,647
onoffonoffon: Acetaminophen (Tyelnol) works by basically blocking the COX from the video (Cox blocked?... anyway...) but it`s not blocking them in the same place. It`s blocking COX enzymes in the central nervous system rather than out at the nociceptors, aka, your spine/brain areas. It`s also not a terribly well understood drug, so there are other things going on there, as well, that are not actually scientifically proven.
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Male 1,647
keith2: Take it with food. Vicodin is made of hydrocodone and.. guess what? Acetaminophen. They hydrocodone messes with your brain`s receptors rather than the active slots on your nociceptors.
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Male 1,647
Draculya: The pharmacist in me cannot let this go as it is. Acetaminophen is NOT an NSAID (Non-steroidal anti-inflammatory drug). It is in fact classified as an analgesic, which does not help inflammation and pretty much just blocks pain.

Fleaman1797: It`s cheap. It does work. It won`t kill you if you don`t take too much of it, much like anything else in life. Don`t use it every time you break a nail, and don`t think you can take a whole load of it at one time and you`ll be fine.
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Male 14,775
"Wish they would have covered Tylenol."

Allow me to do so. Tylenol is a brand of painkiller of varying formulations. Tylenol`s main active ingredient is acetaminophen (a.k.a. paracetamol), which like aspirin and ibuprofen, is classed as a NSAID, although it has weaker anti-inflammatory action. Acetaminophen selectively blocks COX-2 which, as the video says, metabolises arachidonic acid to prostaglandin H2.
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Male 718
No one. NO ONE should take Tylenol. its killed FAR more people then most any other drug and its a worthless HORRIBLE drug. it destroys your liver and its not even for a fair trade (it doesnt work very well) it should be taken off the market, but of course it wont be.
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Male 2,592
This is crap! Yes, I`m being a desk chair warrior here: Most people take tylenol, and naproxin sodium. But they would much rather get their hands on some VICODIN! How does that work? Crap video! Nobody takes asprin or ibuprofen, thats what butthole doctors give you instead of the good stuff. Doesn`t work at all except make your stomach hurt.
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Male 109
The pain causing bunny rabbit attacks again!
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Male 904
About half-way through that video I started to suspect a screamer. What a solid misdirect that would have been.
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Male 36,544
Oooo! Learning is fun!

(I`ve often wondered how this works, thx!)
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Male 2,551
Link: How Pain Relievers Work [Rate Link] - SCIENCE!
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